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Done with first rounds of chemo (Day -9)

26 May 2016
Last Updated: 05 September 2025

Yesterday (Day -10) started out pretty bad. But it ended just fine. Judy went down to the pharmacy and got four bottles of electrolyte drinks, two peach and two coconut. I drank lots of fluids and had lots more infused in my drip. We’re supposed to drink a minimum of three liters of water per day during chemo, and today I clearly met that goal.

I’ve read that there’s a service in Vegas that will bring an I.V. drip to your hotel room if you’ve had a hard night of drinking alcohol. Hmm.

I finished yesterday’s chemo fine, and they gave me a second shot of Amal (anti-chemo-sickness medication) before I left, just for safe keeping. I did need more later, but I ate a pretty large dinner, most of a pre-cooked chicken from Walmart (yes, there's a large Walmart here). I’m already in the “eat carefully” stage where everything needs to be fully-cooked and well-done. We took out the pre-cooked chicken and cooked it even further. Dr. Ruíz said that anything pasteurized is okay, and anything cooked for three full minutes in the microwave should be fine, too. We have our own full-kitchen with a microwave.

This morning, a doctor came by the apartment to give me a subcutaneous shot of Filgrastim, the stem-cell mobilizing agent. This mobilizes the cells out of the bone marrow and into the blood. The drug can become painful to the bones. I’ll be getting these twice-daily for a week now, followed by the harvest (aka apheresis). Apheresis is basically drawing the blood through a glorified centrifuge, which will separate out the blood components by density: white cells, red cells, plasma and stem cells. The stem cells are then cryogenically frozen for Day Zero.

Afterwards, I’ll do two days of strong chemotherapy using mesna and cyclophosphamide. The next day is Day Zero, when I get my stem cells back. Some people start feeling energized with less disability, even before this one hour process is complete. I’ve seen videos online where people clap to your new “birthday” as you return back to the waiting room with the rest of the group. Fifteen of us will have a new, same birthday :).


Important Timeframes

  • My Stem Cell Transplant Date: June 5th, 2016
  • Treatment duration: 4 weeks
  • Typical onset of disability reversal: +9 months
  • Typical complete recovery from procedure: +1 to +2 years
  • Typical maximum reversal of disability: +2 years

Disclaimer

I am not a doctor. I am a scientist (engineer) who has had MS since March 2013.

The website blogs are separated into two sections: the Treatment Blog and the Recovery Blog. Day Zero is when I received my stem cells back.